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HighCostDrugsDemo/data/drug_indication_clusters.csv
T
Andrew Charlwood a31907aa1f feat: complete drug-aware indication matching and cleanup app_v2 
- Remove app_v2.py (consolidated into pathways_app.py), fix __init__ import
- Add DimSearchTerm.csv, drug_indication_clusters.csv, drug_snomed_mapping_enriched.csv
  as reference data for SNOMED-based indication matching
- Add snomed_indication_mapping_query.sql (source for embedded cluster mapping)
- Update DESIGN_SYSTEM.md, RALPH_PROMPT.md, ralph.ps1, uv.lock
2026-02-06 00:33:29 +00:00

12 KiB
Raw Blame History

1DrugIndicationCluster_IDCluster_DescriptionNICE_TA_Reference
2ABATACEPTRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA195/TA280/TA375
3ABATACEPTRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA195/TA280/TA375
4ABATACEPTPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA568
5ACALABRUTINIBChronic lymphocytic leukaemiaCLL_CODChronic lymphocytic leukaemiaTA689
6ADALIMUMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA130/TA195/TA375
7ADALIMUMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA130/TA195/TA375
8ADALIMUMABPsoriasisPSORIASIS_CODPsoriasis codesTA146/TA455
9ADALIMUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA146/TA455
10ADALIMUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA125/TA199
11ADALIMUMABCrohn's diseaseCROHNS_CODCrohn's disease codesTA187
12ADALIMUMABUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA329
13ADALIMUMABAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA143/TA383
14AFLIBERCEPTDiabetic macular oedemaDM_CODDiabetes mellitus codesTA346
15AFLIBERCEPTDiabetic macular oedemaDMTYPE2AUDIT_CODType 2 diabetes codesTA346
16ALIROCUMABHypercholesterolaemiaHYPERCHOL_CODHypercholesterolaemia codesTA393
17APREMILASTPsoriasisPSORIASIS_CODPsoriasis codesTA419
18APREMILASTPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA419
19APREMILASTPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA433
20ATEZOLIZUMABCancer (various)CANCER_CODCancer codes (various)TA492/TA520/TA525
21BARICITINIBRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA466
22BARICITINIBRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA466
23BARICITINIBAtopic dermatitisECZEMA_CODAtopic dermatitis/eczema codesTA681
24BEVACIZUMABCancer (various)CANCER_CODCancer codes (various)TA584/TA666
25BIMEKIZUMABPsoriasisPSORIASIS_CODPsoriasis codesTA723
26BIMEKIZUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA723
27BOTULINUM A TOXINSpasticity (various)SPASTICITY_CODSpasticity and movement disorder codesNo specific TA
28BRODALUMABPsoriasisPSORIASIS_CODPsoriasis codesTA511
29BRODALUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA511
30CERTOLIZUMAB PEGOLRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA375/TA415
31CERTOLIZUMAB PEGOLRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA375/TA415
32CERTOLIZUMAB PEGOLPsoriasisPSORIASIS_CODPsoriasis codesTA574
33CERTOLIZUMAB PEGOLPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA445
34CERTOLIZUMAB PEGOLAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA383
35DENOSUMABOsteoporosisOSTEO_CODOsteoporosis codesTA204
36DENOSUMABBone metastasesCANCER_CODCancer codes (bone metastases)TA265
37DEXAMETHASONEDiabetic macular oedemaDM_CODDiabetes mellitus codesTA349/TA824
38DEXAMETHASONEDiabetic macular oedemaDMTYPE2AUDIT_CODType 2 diabetes codesTA349/TA824
39DEXAMETHASONEMultiple myelomaMM_CODMultiple myeloma codesTA311/TA380
40DEXAMETHASONEUveitisUVEITIS_CODUveitis codesTA460
41DIMETHYL FUMARATEMultiple sclerosisMS_CODMultiple sclerosis codesTA320
42DIMETHYL FUMARATEPsoriasisPSORIASIS_CODPsoriasis codesTA475
43DOCETAXELCancer (various)CANCER_CODCancer codes (breast/lung/prostate)TA006/TA030/TA101
44DUPILUMABAtopic dermatitisECZEMA_CODAtopic dermatitis/eczema codesTA534
45DUPILUMABAsthmaASTHMA_CODAsthma codesTA751
46ERENUMABMigraineMIGRAINE_CODMigraine codesTA682
47ETANERCEPTRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA036/TA130/TA195
48ETANERCEPTRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA036/TA130/TA195
49ETANERCEPTPsoriasisPSORIASIS_CODPsoriasis codesTA103
50ETANERCEPTPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA103
51ETANERCEPTPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA104/TA199
52ETANERCEPTAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA143/TA383
53EVOLOCUMABHypercholesterolaemiaHYPERCHOL_CODHypercholesterolaemia codesTA394
54FARICIMABDiabetic macular oedemaDM_CODDiabetes mellitus codesTA799
55FARICIMABDiabetic macular oedemaDMTYPE2AUDIT_CODType 2 diabetes codesTA799
56FILGOTINIBRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA676
57FILGOTINIBRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA676
58FILGOTINIBUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA792
59FLUOCINOLONEAtopic dermatitisECZEMA_CODAtopic dermatitis/eczema codesTA081
60FLUOCINOLONEDiabetic macular oedemaDM_CODDiabetes mellitus codesTA301
61FLUOCINOLONEUveitisUVEITIS_CODUveitis codesTA590
62FLUOCINOLONE ACETONIDEAtopic dermatitisECZEMA_CODAtopic dermatitis/eczema codesTA081
63FLUOCINOLONE ACETONIDEDiabetic macular oedemaDM_CODDiabetes mellitus codesTA301
64FLUOCINOLONE ACETONIDEUveitisUVEITIS_CODUveitis codesTA590
65FREMANEZUMABMigraineMIGRAINE_CODMigraine codesTA631/TA764
66GALCANEZUMABMigraineMIGRAINE_CODMigraine codesTA659
67GOLIMUMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA225/TA375
68GOLIMUMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA225/TA375
69GOLIMUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA220
70GOLIMUMABUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA329
71GOLIMUMABAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA233/TA383
72GUSELKUMABPsoriasisPSORIASIS_CODPsoriasis codesTA521
73GUSELKUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA521
74GUSELKUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA711/TA815
75IDARUCIZUMABAnticoagulant reversalANTICOAG_CODAnticoagulation-related codesNo specific TA
76IMATINIBChronic myeloid leukaemiaCML_CODChronic myeloid leukaemia codesTA050/TA070/TA251
77IMATINIBGastrointestinal stromal tumoursGIST_CODGastrointestinal stromal tumour codesTA086/TA326
78IMMUNOGLOBULINImmunodeficiency (various)IMMUNODEF_CODPrimary/secondary immunodeficiency codesTA481/TA482
79INFLIXIMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA036/TA130/TA195
80INFLIXIMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA036/TA130/TA195
81INFLIXIMABPsoriasisPSORIASIS_CODPsoriasis codesTA134
82INFLIXIMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA134
83INFLIXIMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA104/TA199
84INFLIXIMABCrohn's diseaseCROHNS_CODCrohn's disease codesTA040/TA187
85INFLIXIMABUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA163/TA329
86INFLIXIMABAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA383
87IXEKIZUMABPsoriasisPSORIASIS_CODPsoriasis codesTA442
88IXEKIZUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA442
89IXEKIZUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA537
90IXEKIZUMABAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA718
91LUCENTISDiabetic macular oedemaDM_CODDiabetes mellitus codesBiosimilar of ranibizumab
92LUCENTISDiabetic macular oedemaDMTYPE2AUDIT_CODType 2 diabetes codesBiosimilar of ranibizumab
93OBINUTUZUMABChronic lymphocytic leukaemiaCLL_CODChronic lymphocytic leukaemia codesTA343/TA663
94OBINUTUZUMABFollicular lymphomaFL_CODFollicular lymphoma codesTA472/TA513/TA629
95OCTREOTIDENeuroendocrine tumoursNET_CODNeuroendocrine tumour codesNo specific TA
96OMALIZUMABAsthmaASTHMA_CODAsthma codesTA133/TA278
97OMALIZUMABChronic urticariaURTICARIA_CODUrticaria codesTA339
98RANIBIZUMABDiabetic macular oedemaDM_CODDiabetes mellitus codesTA274
99RANIBIZUMABDiabetic macular oedemaDMTYPE2AUDIT_CODType 2 diabetes codesTA274
100REMICADERheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesBrand name for infliximab
101REMICADECrohn's diseaseCROHNS_CODCrohn's disease codesBrand name for infliximab
102REMICADEUlcerative colitisULCCOLITIS_CODUlcerative colitis codesBrand name for infliximab
103REMICADEPsoriasisPSORIASIS_CODPsoriasis codesBrand name for infliximab
104RILUZOLEMotor neurone diseaseMND_CODMotor neurone disease codesTA020
105RISANKIZUMABPsoriasisPSORIASIS_CODPsoriasis codesTA596
106RISANKIZUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA596
107RISANKIZUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA803
108RITUXIMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA126/TA195
109RITUXIMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA126/TA195
110RITUXIMABNon-Hodgkin's lymphomaNHL_CODNon-Hodgkin's lymphoma codesTA037/TA065/TA110
111RITUXIMABChronic lymphocytic leukaemiaCLL_CODChronic lymphocytic leukaemia codesTA174/TA193/TA359
112RITUXIMABANCA-associated vasculitisVASCULITIS_CODVasculitis codesTA308
113RIXATHONRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesBiosimilar of rituximab
114RIXATHONNon-Hodgkin's lymphomaNHL_CODNon-Hodgkin's lymphoma codesBiosimilar of rituximab
115SACITUZUMABTriple-negative breast cancerBREASTCA_CODBreast cancer codesTA819
116SARILUMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA485
117SARILUMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA485
118SECUKINUMABPsoriasisPSORIASIS_CODPsoriasis codesTA350/TA734
119SECUKINUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA350/TA734
120SECUKINUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA445
121SECUKINUMABAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA407/TA719
122TERIPARATIDEOsteoporosisOSTEO_CODOsteoporosis codesTA087/TA161
123TILDRAKIZUMABPsoriasisPSORIASIS_CODPsoriasis codesNo TA match found
124TILDRAKIZUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)No TA match found
125TOCILIZUMABRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA198/TA247/TA375
126TOCILIZUMABRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA198/TA247/TA375
127TOCILIZUMABJuvenile idiopathic arthritisJIA_CODJuvenile idiopathic arthritis codesTA238/TA373
128TOCILIZUMABGiant cell arteritisGCA_CODGiant cell arteritis codesTA518
129TOFACITINIBRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA480
130TOFACITINIBRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA480
131TOFACITINIBPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA543
132TOFACITINIBUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA547
133UPADACITINIBRheumatoid arthritisRARTH_CODRheumatoid arthritis diagnosis codesTA665/TA744
134UPADACITINIBRheumatoid arthritisC19RARTH_CODRheumatoid arthritis disorders (broader)TA665/TA744
135UPADACITINIBPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA768
136UPADACITINIBAtopic dermatitisECZEMA_CODAtopic dermatitis/eczema codesTA814
137UPADACITINIBAnkylosing spondylitisANKSPON_CODAnkylosing spondylitis codesTA829
138UPADACITINIBUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA856
139USTEKINUMABPsoriasisPSORIASIS_CODPsoriasis codesTA180/TA455
140USTEKINUMABPsoriasisCUST_CMMS_PSORIASISPsoriasis (Cambridge Multimorbidity)TA180/TA455
141USTEKINUMABPsoriatic arthritisPSORIASIS_CODPsoriasis codes (for psoriatic arthritis)TA340
142USTEKINUMABCrohn's diseaseCROHNS_CODCrohn's disease codesTA456
143USTEKINUMABUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA633
144VEDOLIZUMABUlcerative colitisULCCOLITIS_CODUlcerative colitis codesTA342
145VEDOLIZUMABCrohn's diseaseCROHNS_CODCrohn's disease codesTA352
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