Remove claude working folders

This commit is contained in:
Andrew Charlwood
2026-02-10 15:30:27 +00:00
parent f96950111b
commit a496c01eb4
4 changed files with 19 additions and 704 deletions
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"Read",
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"Bash(Remove-Item -Path \"C:\\\\Users\\\\charlwoodand\\\\Ralph local\\\\Tasks\\\\UI Redesign\\\\logs\\\\*\" -Force)",
"Bash(git commit -m \"$\\(cat <<''EOF''\ndocs: update CLAUDE.md to reflect slimmed database architecture\n\nRemove references to deleted tables \\(fact_interventions,\nmv_patient_treatment_summary, ref_drug_snomed_mapping, processed_files\\),\ndeleted files \\(patient_data.py, load_snomed_mapping.py\\), and removed\nclasses \\(SQLiteDataLoader\\). Update package structure, data loaders,\ndatabase schema, fallback chain, and AppState descriptions.\nEOF\n\\)\")",
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+19 -1
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@@ -9,6 +9,7 @@ build/
dist/ dist/
wheels/ wheels/
*.egg-info *.egg-info
*claude*
# Virtual environments # Virtual environments
.venv .venv
@@ -32,10 +33,27 @@ hcd_20250411.parquet
logs/*.log logs/*.log
logs/*.jsonl logs/*.jsonl
# Reflex build artifacts (future) # Reflex build artifacts (legacy)
.web/ .web/
.states/ .states/
# Legacy files (old Reflex/CustomTkinter app)
archive/
images/
run.bat
# Ralph loop files
ralph.ps1
RALPH_PROMPT.md
progress.txt
# Planning/process docs (not used by application)
guardrails.md
IMPLEMENTATION_PLAN.md
# Windows artifacts
NUL
# SQLite databases (except pathways.db which contains pre-computed data) # SQLite databases (except pathways.db which contains pre-computed data)
*.db *.db
!data/pathways.db !data/pathways.db
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# CLAUDE.md
This file provides guidance to Claude Code (claude.ai/code) when working with code in this repository.
## Project Overview
NHS High-Cost Drug Patient Pathway Analysis Tool - a web-based application that analyzes secondary care patient treatment pathways. It processes clinical activity data to visualize hierarchical treatment patterns as interactive Plotly icicle charts.
**Key Features:**
- **Dual chart types**: Directory-based (Trust → Directory → Drug → Pathway) and Indication-based (Trust → GP Diagnosis → Drug → Pathway) views with toggle
- **Pre-computed pathway architecture**: Treatment pathways pre-processed and stored in SQLite for instant filtering
- **GP diagnosis matching**: Patient indications matched from GP records using SNOMED cluster codes queried directly from Snowflake (~93% match rate)
- Data pipeline: Snowflake → pre-computed SQLite pathway nodes (CSV/Parquet file loading retained for legacy compatibility)
- Interactive browser-based UI using Dash (Plotly) + Dash Mantine Components
- 6 pre-defined date filter combinations × 2 chart types = 12 pre-computed datasets with sub-50ms response times
## Running the Application
```bash
# Install dependencies
uv sync
# One-time dev setup: adds src/ to Python path via .pth file
uv run python setup_dev.py
# Initialize/migrate the database (creates pathway tables)
python -m data_processing.migrate
# Refresh pathway data from Snowflake (requires SSO auth)
python -m cli.refresh_pathways
# Run the Dash web application
python run_dash.py
```
The application requires Python 3.10+ and runs on http://localhost:8050 by default.
### CLI Commands
**Refresh Pathway Data:**
```bash
# Full refresh — both chart types (directory + indication), all date filters
python -m cli.refresh_pathways --chart-type all
# Directory charts only (faster, skips GP diagnosis lookup)
python -m cli.refresh_pathways --chart-type directory
# Indication charts only
python -m cli.refresh_pathways --chart-type indication
# Dry run (test without database changes)
python -m cli.refresh_pathways --chart-type all --dry-run -v
# Custom minimum patient threshold
python -m cli.refresh_pathways --minimum-patients 10
# Help
python -m cli.refresh_pathways --help
```
The `--chart-type` argument controls which pathway types are processed:
- `all` (default) — generates both directory and indication charts (~15 minutes)
- `directory` — directory-based charts only (~5 minutes)
- `indication` — indication-based charts only (~12 minutes, includes GP lookup)
The refresh command:
1. Fetches activity data from Snowflake (656K+ records, ~7 seconds)
2. Applies UPID, drug name, and directory transformations (~6 minutes)
3. For indication charts: queries GP records via SNOMED clusters (~9 minutes for 37K patients)
4. Processes 6 date filter combinations × selected chart types
5. Inserts pathway nodes to SQLite for fast Dash filtering
## Architecture
### Package Structure
```
.
├── src/ # All application library code
│ ├── core/ # Foundation: paths, models, logging
│ │ ├── config.py # PathConfig dataclass for file paths
│ │ ├── models.py # AnalysisFilters dataclass
│ │ └── logging_config.py # Structured logging setup
│ │
│ ├── config/ # Service configuration
│ │ ├── __init__.py # SnowflakeConfig + loader
│ │ └── snowflake.toml # Connection settings (co-located with loader)
│ │
│ ├── data_processing/ # Data layer
│ │ ├── database.py # SQLite connection management
│ │ ├── schema.py # Database schema (reference + pathway tables)
│ │ ├── pathway_pipeline.py # Pipeline: Snowflake → SQLite
│ │ ├── transforms.py # Data transformations (UPID, drug names, directory)
│ │ ├── loader.py # FileDataLoader for CSV/Parquet files
│ │ ├── reference_data.py # Reference data migration
│ │ ├── snowflake_connector.py # Snowflake integration
│ │ ├── cache.py # Query result caching
│ │ ├── data_source.py # Data source fallback chain
│ │ ├── diagnosis_lookup.py # GP diagnosis lookup (SNOMED clusters)
│ │ └── parsing.py # Parse average_spacing HTML, pathway drugs, retention rates
│ │
│ ├── analysis/ # Analysis pipeline
│ │ ├── pathway_analyzer.py # prepare_data, calculate_statistics, build_hierarchy
│ │ └── statistics.py # Statistical calculation functions
│ │
│ ├── visualization/ # Chart generation
│ │ └── plotly_generator.py # Icicle, market share, cost effectiveness, waterfall, Sankey, dosing, heatmap, duration figures
│ │
│ └── cli/ # CLI tools
│ └── refresh_pathways.py # Data refresh command
├── dash_app/ # Dash web application
│ ├── app.py # Dash app, layout root, dcc.Store, register_callbacks
│ ├── assets/
│ │ └── nhs.css # NHS design system CSS
│ ├── data/
│ │ ├── queries.py # Thin wrapper calling src/data_processing/pathway_queries.py
│ │ └── card_browser.py # DimSearchTerm.csv → directorate tree for modals
│ ├── components/
│ │ ├── header.py # Top header bar with fraction KPIs + data freshness
│ │ ├── sidebar.py # Left nav: Patient Pathways + Trust Comparison
│ │ ├── sub_header.py # Global filter bar (date dropdowns + chart type toggle)
│ │ ├── filter_bar.py # Patient Pathways filter buttons (drugs, trusts, directorates)
│ │ ├── chart_card.py # Chart area with Icicle/Sankey tabs + dcc.Graph
│ │ ├── modals.py # dmc.Modal dialogs for drug/trust/directorate selection
│ │ ├── trust_comparison.py # Trust Comparison landing page + 6-chart dashboard
│ │ └── footer.py # Page footer
│ ├── callbacks/
│ │ ├── __init__.py # register_callbacks(app)
│ │ ├── filters.py # Reference data loading + filter state management
│ │ ├── chart.py # Tab switching, pathway data loading, chart dispatch
│ │ ├── modals.py # Modal open/close + drug/trust/directorate selection
│ │ ├── navigation.py # Sidebar view switching + Trust Comparison navigation
│ │ ├── trust_comparison.py # 6 Trust Comparison chart callbacks
│ │ └── kpi.py # Header fraction KPI updates
│ └── utils/
│ └── __init__.py
├── run_dash.py # Entry point: python run_dash.py
├── tests/ # Test suite (113 tests)
├── data/ # Reference data + SQLite DB
├── docs/ # Documentation
├── assets/ # Static assets (logo, favicon)
├── archive/ # Historical/deprecated (includes old Reflex app)
└── logs/ # Runtime logs
```
**Path resolution**: `src/` is added to `sys.path` via a `.pth` file (created by `setup_dev.py`).
All imports use package names directly: `from core import ...`, `from data_processing import ...`, etc.
### Pathway Data Architecture
The application uses a pre-computed pathway architecture for performance:
**Architecture:** `Snowflake → Pathway Processing → SQLite (pre-computed) → Dash (filter & view)`
**Key Benefits:**
- **Performance**: Pathway calculation done once during data refresh, not on every filter change
- **Simplicity**: Dash callbacks filter pre-computed data with simple SQL WHERE clauses
- **Full Pathways**: Sequential treatment pathways (drug_0 → drug_1 → drug_2...) with statistics
**Chart Types:**
| Type | Hierarchy | Level 2 Source |
|------|-----------|----------------|
| `directory` | Trust → Directory → Drug → Pathway | Assigned directorate (5-level fallback) |
| `indication` | Trust → GP Diagnosis → Drug → Pathway | SNOMED cluster Search_Term from GP records |
For indication charts, ~93% of patients are matched to a GP diagnosis (Search_Term). Unmatched patients use their directorate as a fallback label (e.g., "RHEUMATOLOGY (no GP dx)").
**Date Filter Combinations:**
| ID | Initiated | Last Seen | Default |
|----|-----------|-----------|---------|
| `all_6mo` | All years | Last 6 months | Yes |
| `all_12mo` | All years | Last 12 months | No |
| `1yr_6mo` | Last 1 year | Last 6 months | No |
| `1yr_12mo` | Last 1 year | Last 12 months | No |
| `2yr_6mo` | Last 2 years | Last 6 months | No |
| `2yr_12mo` | Last 2 years | Last 12 months | No |
Total pre-computed datasets: 6 date filters × 2 chart types = 12 datasets (~3,600 pathway nodes).
**Pathway Node Structure:**
Each node in `pathway_nodes` contains:
- Routing: `chart_type` ("directory" or "indication"), `date_filter_id`
- Hierarchy: `parents`, `ids`, `labels`, `level` (0=Root, 1=Trust, 2=Directory/Indication, 3=Drug, 4+=Pathway)
- Counts: `value` (patient count)
- Costs: `cost`, `costpp`, `cost_pp_pa` (per patient per annum)
- Dates: `first_seen`, `last_seen`, `first_seen_parent`, `last_seen_parent`
- Statistics: `average_spacing`, `average_administered`, `avg_days`
- Denormalized: `trust_name`, `directory`, `drug_sequence` (for efficient filtering)
- Unique constraint: `UNIQUE(date_filter_id, chart_type, ids)`
### Core Module (`core/`)
- **PathConfig** - Dataclass encapsulating all file paths, with `validate()` method
- **AnalysisFilters** - Dataclass for filter state (dates, drugs, trusts, directories)
- **logging_config** - Structured logging with file and console output
### CLI Module (`cli/`)
- **refresh_pathways.py** - Command-line tool to refresh pre-computed pathway data:
- `refresh_pathways()` - Main function orchestrating the full pipeline
- `insert_pathway_records()` - SQLite insertion with parameterized queries
- `log_refresh_start/complete/failed()` - Refresh tracking in `pathway_refresh_log`
- `get_default_filters()` - Load trusts/drugs/directories from CSV files
### Data Processing Module (`data_processing/`)
**Database Management:**
- `DatabaseManager` - SQLite connection pooling and transaction management
- **Reference Tables**: `ref_drug_names`, `ref_organizations`, `ref_directories`, `ref_drug_directory_map`, `ref_drug_indication_clusters`
- **Pathway Tables**: `pathway_date_filters`, `pathway_nodes`, `pathway_refresh_log`
**Pathway Pipeline (`pathway_pipeline.py`):**
- `DateFilterConfig` - Dataclass for date filter configuration
- `DATE_FILTER_CONFIGS` - All 6 pre-defined date combinations
- `compute_date_ranges(config, max_date)` - Computes actual ISO dates from config
- `fetch_and_transform_data()` - Snowflake fetch + UPID/drug/directory transformations
- Directory chart functions:
- `process_pathway_for_date_filter()` - Processes single date filter using `generate_icicle_chart()`
- `extract_denormalized_fields()` - Parses `ids` column to extract trust, directory, drug_sequence
- Indication chart functions:
- `process_indication_pathway_for_date_filter()` - Processes single date filter using `generate_icicle_chart_indication()`
- `extract_indication_fields()` - Parses `ids` for indication charts (trust, search_term, drug_sequence)
- Shared functions:
- `convert_to_records(ice_df, chart_type)` - Converts ice_df to list of dicts with `chart_type` column
- `process_all_date_filters()` - Convenience function to process all 6 filters
**Data Loaders:**
- `FileDataLoader` - Loads from CSV/Parquet files (used by legacy pipeline, not by Dash app)
- Factory function `get_loader()` creates a `FileDataLoader`
**Snowflake Integration:**
- SSO authentication via `externalbrowser` authenticator
- `fetch_activity_data(start_date, end_date, provider_codes)` method
- Query caching with TTL-based invalidation
**GP Diagnosis Lookup (`diagnosis_lookup.py`):**
- `CLUSTER_MAPPING_SQL` - Embedded SQL constant with ~148 Search_Term → Cluster_ID mappings plus explicit SNOMED codes
- `get_patient_indication_groups(patient_pseudonyms)` - Batch queries Snowflake to match patients to GP diagnoses:
- Embeds cluster mapping as CTE, joins with `PrimaryCareClinicalCoding`
- Uses `PseudoNHSNoLinked` (not PersonKey) to match `PatientPseudonym` in GP records
- Returns most recent match per patient via `QUALIFY ROW_NUMBER()`
- Batches 500 patients per query, returns DataFrame with PatientPseudonym, Search_Term, EventDateTime
- `patient_has_indication(patient_pseudonym, cluster_ids)` - Single-patient GP record check (legacy)
- `validate_indication(patient_pseudonym, drug_name)` - Full validation result with source tracking (legacy)
### Analysis Module (`analysis/`)
Refactored from the original 267-line `generate_graph()` function:
- **prepare_data()** - Filter DataFrame by date range, trusts, drugs, directories (copies df to prevent mutation)
- **calculate_statistics()** - Compute frequency, cost, duration statistics
- **build_hierarchy()** - Create Trust → Directory → Drug → Pathway structure
- **prepare_chart_data()** - Format data for Plotly icicle chart
- **generate_icicle_chart_indication(df, indication_df, ...)** - Build indication-based hierarchy using Search_Term instead of Directory. Takes an `indication_df` (UPID → Search_Term mapping) alongside the main activity DataFrame.
### Visualization Module (`visualization/`)
- **create_icicle_figure(ice_df)** - Generate Plotly icicle chart from DataFrame (legacy/pipeline use)
- **create_icicle_from_nodes(nodes, title)** - Generate icicle chart from list-of-dicts (Dash use). Accepts JSON-serializable node dicts from `dcc.Store`. Uses NHS blue gradient colorscale, 10-field customdata, Source Sans 3 font.
- **create_market_share_figure(data, title)** - Horizontal stacked bar chart: drugs grouped by directorate/indication, bar length = % patients
- **create_cost_effectiveness_figure(data, retention, title)** - Lollipop chart: pathway cost_pp_pa with dot size = patient count, retention annotations
- **create_cost_waterfall_figure(data, title)** - Waterfall chart: directorate-level cost_pp_pa sorted highest to lowest
- **create_sankey_figure(data, title)** - Sankey diagram: drug switching flows across treatment lines (1st → 2nd → 3rd)
- **create_dosing_figure(data, title, group_by)** - Grouped horizontal bar chart: dosing intervals by drug or trust
- **create_heatmap_figure(data, title, metric)** - Matrix heatmap: directorate × drug with patient/cost/cost_pp_pa colouring
- **create_duration_figure(data, title, show_directory)** - Horizontal bar chart: average treatment duration in days per drug
- **create_trust_market_share_figure(data, title)** - Trust Comparison: horizontal stacked bars grouped by trust, drugs as segments
- **create_trust_heatmap_figure(data, title, metric)** - Trust Comparison: trust × drug matrix with NHS blue colorscale
- **create_trust_duration_figure(data, title)** - Trust Comparison: grouped horizontal bars with one trace per trust
- **save_figure_html()** - Save interactive HTML file
- **open_figure_in_browser()** - Open chart in default browser
### Parsing Utilities (`data_processing/parsing.py`)
- **parse_average_spacing(spacing_html)** - Extract drug_name, dose_count, weekly_interval, total_weeks from HTML string
- **parse_pathway_drugs(ids, level)** - Extract ordered drug list from ids column at level 4+
- **calculate_retention_rate(nodes)** - For each N-drug pathway, calculate % not escalating to N+1 drugs
### Shared Data Queries (`data_processing/pathway_queries.py`)
Shared query functions used by the Dash app (via thin wrappers in `dash_app/data/queries.py`):
- **load_initial_data(db_path)** - Returns available drugs (42), directorates (14), indications (32), trusts (7), total_patients, last_updated
- **load_pathway_nodes(db_path, filter_id, chart_type, selected_drugs, selected_directorates, selected_trusts)** - Returns pathway nodes, unique_patients, total_drugs, total_cost, last_updated. Parameterized SQL with optional drug/directorate/trust filters.
- **get_drug_market_share(db_path, filter_id, chart_type, directory, trust)** - Level 3 nodes grouped by directory, returns drug, value, colour
- **get_pathway_costs(db_path, filter_id, chart_type, directory, trust)** - Level 4+ nodes with cost_pp_pa, pathway labels, patient counts
- **get_cost_waterfall(db_path, filter_id, chart_type, trust)** - Level 2 nodes with cost_pp_pa per directorate/indication
- **get_drug_transitions(db_path, filter_id, chart_type, directory, trust)** - Level 3+ nodes parsed into source→target drug transitions
- **get_dosing_intervals(db_path, filter_id, chart_type, drug, trust)** - Level 3 nodes with parsed average_spacing intervals
- **get_drug_directory_matrix(db_path, filter_id, chart_type, trust)** - Level 3 nodes pivoted as directory × drug matrix
- **get_treatment_durations(db_path, filter_id, chart_type, directory, trust)** - Level 3 nodes with avg_days by drug
- **get_trust_market_share(db_path, filter_id, chart_type, directory)** - Trust Comparison: drugs by trust within a single directorate
- **get_trust_cost_waterfall(db_path, filter_id, chart_type, directory)** - Trust Comparison: one bar per trust showing cost_pp within directorate
- **get_trust_dosing(db_path, filter_id, chart_type, directory)** - Trust Comparison: drug dosing intervals broken down by trust
- **get_trust_heatmap(db_path, filter_id, chart_type, directory)** - Trust Comparison: trust × drug matrix for one directorate
- **get_trust_durations(db_path, filter_id, chart_type, directory)** - Trust Comparison: drug durations by trust within directorate
- **get_directorate_summary(db_path, filter_id, chart_type, directory)** - Summary stats for a directorate (total patients, drugs, cost)
### Dash Application (`dash_app/`)
**Two-View Architecture:**
The application is split into two analytical perspectives, selectable via the sidebar:
- **Patient Pathways**: Pathway-focused analysis (Icicle + Sankey charts) with drug/trust/directorate filters
- **Trust Comparison**: Per-directorate analysis comparing drugs across trusts (6 charts for a selected directorate)
**State Management** via 4 `dcc.Store` components:
- **app-state** (session): `chart_type`, `initiated`, `last_seen`, `date_filter_id`, `selected_drugs`, `selected_directorates`, `selected_trusts`, `active_view` ("patient-pathways" | "trust-comparison"), `selected_comparison_directorate` (null | directorate name)
- **chart-data** (memory): `nodes[]`, `unique_patients`, `total_drugs`, `total_cost`, `last_updated`
- **reference-data** (session): `available_drugs`, `available_directorates`, `available_indications`, `available_trusts`, `total_patients`, `last_updated`
- **active-tab** (memory): Currently selected chart tab within Patient Pathways ("icicle" | "sankey")
**Callback Chain** (unidirectional):
```
Page Load → load_reference_data → reference-data store + header indicators
→ update_app_state → app-state store (default filters)
→ load_pathway_data → chart-data store
├→ update_kpis → header fraction KPIs
└→ update_chart → dcc.Graph (Icicle or Sankey)
Filter change → update_app_state → app-state → load_pathway_data → (chain above)
Modal selection → drug/trust chips → update_app_state → (chain above)
Tab click → switch_tab → active-tab store → update_chart → dcc.Graph (lazy rendering)
Sidebar click → switch_view → active_view in app-state → show/hide views
Trust Comparison:
Landing page → directorate button click → selected_comparison_directorate → 6 chart callbacks
Back button → clear selected_comparison_directorate → return to landing
```
**Key Components:**
- **Header** (`header.py`): NHS branding, fraction KPIs (X/X patients, X/X drugs, £X/£X cost), data freshness indicator
- **Sidebar** (`sidebar.py`): 2 navigation items — "Patient Pathways" (default), "Trust Comparison"
- **Sub-Header** (`sub_header.py`): Global filter bar — date dropdowns (Initiated, Last Seen) + chart type toggle pills (By Directory / By Indication). Constant across both views.
- **Filter Bar** (`filter_bar.py`): Patient Pathways-only filter buttons — Drugs (with count badge), Trusts (with count badge), Directorates (with count badge), Clear All. Only visible on Patient Pathways view.
- **Chart Card** (`chart_card.py`): 2-tab chart area (Icicle, Sankey) with `dcc.Loading` spinner, dynamic subtitle, and `dcc.Store(id="active-tab")`
- **Modals** (`modals.py`): 3 `dmc.Modal` dialogs for drug selection (ChipGroup), trust selection (ChipGroup), directorate browser (Accordion with indication sub-items and drug fragment badges)
- **Trust Comparison** (`trust_comparison.py`): Landing page (directorate/indication button grid) + 6-chart dashboard (Market Share, Cost Waterfall, Dosing, Heatmap, Duration, Cost Effectiveness)
- **Footer** (`footer.py`): NHS Norfolk and Waveney ICB branding
**Filter Modals:**
- Drug Modal: flat `dmc.ChipGroup` with 42 drugs from pathway_nodes level 3
- Trust Modal: `dmc.ChipGroup` with 7 trusts
- Directorate Modal: nested `dmc.Accordion` — 19 directorates → indications → drug fragment `dmc.Badge` items
- Clicking a drug fragment badge selects all full drug names containing that fragment (substring match)
- "Clear All Filters" button resets drug and trust selections
**Trust Comparison Dashboard (6 Charts):**
All scoped to a single selected directorate, comparing drugs across trusts:
1. **Market Share**: Drug breakdown per trust (stacked bars per trust)
2. **Cost Waterfall**: Per-trust cost within directorate
3. **Dosing**: Drug dosing intervals by trust
4. **Heatmap**: Trust × drug matrix
5. **Duration**: Drug durations by trust
6. **Cost Effectiveness**: Pathway costs within directorate (NOT split by trust)
### Data Transformations (`data_processing/transforms.py`)
Core data transformation functions used by the pipeline:
- `patient_id()` - Creates UPID = Provider Code (first 3 chars) + PersonKey
- `drug_names()` - Standardizes via drugnames.csv lookup
- `department_identification()` - 5-level fallback chain for directory assignment
### Data Flow
**Pre-Computed Pathway Architecture (Current):**
```
[CLI: python -m cli.refresh_pathways --chart-type all]
Snowflake Data Warehouse
▼ (fetch_and_transform_data)
┌──────────────────────────────────────────┐
│ Data Transformations (data_processing/transforms.py) │
│ → patient_id() creates UPID │
│ → drug_names() standardizes names │
│ → department_identification() → Dir │
└──────────────────────────────────────────┘
├─── Directory Charts ──────────────────────────────────────┐
│ │
│ ┌──────────────────────────────────────────┐ │
│ │ For each of 6 date filter combos: │ │
│ │ → generate_icicle_chart() │ │
│ │ → extract_denormalized_fields() │ │
│ │ → convert_to_records("directory") │ │
│ └──────────────────────────────────────────┘ │
│ │
├─── Indication Charts ─────────────────────────────────────┤
│ │
│ ┌──────────────────────────────────────────┐ │
│ │ GP Diagnosis Lookup (diagnosis_lookup.py)│ │
│ │ → Extract PseudoNHSNoLinked from HCD │ │
│ │ → get_patient_indication_groups() │ │
│ │ (SNOMED cluster CTE + GP records) │ │
│ │ → Build indication_df: UPID → Search │ │
│ │ Term (matched) or Directorate (no GP)│ │
│ └──────────────────────────────────────────┘ │
│ │ │
│ ▼ │
│ ┌──────────────────────────────────────────┐ │
│ │ For each of 6 date filter combos: │ │
│ │ → generate_icicle_chart_indication() │ │
│ │ → extract_indication_fields() │ │
│ │ → convert_to_records("indication") │ │
│ └──────────────────────────────────────────┘ │
│ │
└───────────────────────┬───────────────────────────────────┘
▼ (insert_pathway_records)
┌──────────────────────────────────────────┐
│ SQLite: pathway_nodes table │
│ → ~3,600 nodes across 12 datasets │
│ → UNIQUE(date_filter_id, chart_type, │
│ ids) prevents cross-type overwrites │
│ → Indexed for fast filtering │
└──────────────────────────────────────────┘
[Dash App: python run_dash.py]
┌──────────────────────────────────────────┐
│ Global Sub-Header (date dropdowns, │
│ chart type toggle pills) │
│ → Triggers update_app_state callback │
└──────────────────────────────────────────┘
├─── Patient Pathways View ─────────────────────────────┐
│ │
│ ┌──────────────────────────────────────────┐ │
│ │ Filter Bar (Drugs/Trusts/Directorates) │ │
│ │ → Modal selections → app-state │ │
│ └──────────────────────────────────────────┘ │
│ │ │
│ ▼ │
│ ┌──────────────────────────────────────────┐ │
│ │ load_pathway_data callback │ │
│ │ → chart-data store │ │
│ └──────────────────────────────────────────┘ │
│ │ │
│ ├──────────────────────────────┐ │
│ ▼ ▼ │
│ ┌────────────────────┐ ┌──────────────────────┐ │
│ │ update_kpis │ │ update_chart │ │
│ │ → header KPIs │ │ → Icicle or Sankey │ │
│ └────────────────────┘ └──────────────────────┘ │
│ │
├─── Trust Comparison View ─────────────────────────────┤
│ │
│ ┌──────────────────────────────────────────┐ │
│ │ Landing Page │ │
│ │ → Directorate/Indication buttons │ │
│ │ → Click → selected_comparison_dir │ │
│ └──────────────────────────────────────────┘ │
│ │ │
│ ▼ │
│ ┌──────────────────────────────────────────┐ │
│ │ 6-Chart Dashboard │ │
│ │ → Market Share, Cost Waterfall, Dosing │ │
│ │ → Heatmap, Duration, Cost Effectiveness│ │
│ │ → All per-trust within one directorate │ │
│ └──────────────────────────────────────────┘ │
│ │
└────────────────────────────────────────────────────────┘
```
### Reference Data Files (`data/`)
| File | Purpose |
|------|---------|
| `include.csv` | Drug filter list with default selections (Include=1) |
| `defaultTrusts.csv` | NHS Trust list for filter |
| `directory_list.csv` | Medical specialties/directories |
| `drugnames.csv` | Drug name standardization mapping |
| `org_codes.csv` | Provider code to organization name mapping |
| `drug_directory_list.csv` | Valid drug-to-directory mappings (pipe-separated) |
| `treatment_function_codes.csv` | NHS treatment function code mappings |
| `drug_indication_clusters.csv` | Drug to SNOMED cluster mappings |
| `ta-recommendations.xlsx` | NICE TA recommendations |
| `pathways.db` | SQLite database (~3.5 MB: reference tables + pathway nodes) |
### Key Patterns
**Department Identification Fallback Chain:**
The `department_identification()` function has 5 levels of fallback:
1. **SINGLE_VALID_DIR** - Drug has only one valid directory
2. **EXTRACTED** - Extracted from Additional Detail/Description fields
3. **CALCULATED_MOST_FREQ** - Most frequent valid directory for UPID/Drug
4. **UPID_INFERENCE** - Inferred from other records with same UPID
5. **UNDEFINED** - No directory could be determined
**Indication Lookup Workflow (for indication charts):**
1. Extract unique `PseudoNHSNoLinked` values from HCD activity data
2. Query Snowflake in batches of 500 patients:
- Embed `CLUSTER_MAPPING_SQL` (~148 Search_Term → Cluster_ID mappings) as CTE
- Join `ClinicalCodingClusterSnomedCodes` to get SNOMED codes per cluster
- Join `PrimaryCareClinicalCoding` on `PatientPseudonym` = `PseudoNHSNoLinked`
- Use `QUALIFY ROW_NUMBER() OVER (PARTITION BY PatientPseudonym ORDER BY EventDateTime DESC) = 1` for most recent match
3. Build `indication_df` mapping UPID → Search_Term (matched) or Directorate + " (no GP dx)" (unmatched)
4. Pass to `generate_icicle_chart_indication()` for pathway hierarchy building
**Data Source Fallback Chain** (for raw data loading, not used by Dash app):
1. Query cache for recent results
2. Attempt Snowflake connection
3. Fall back to CSV/Parquet files
## Database Schema (~3.5 MB)
### Reference Tables
- `ref_drug_names` - Drug name standardization
- `ref_organizations` - Provider code to name mapping
- `ref_directories` - Valid directory names
- `ref_drug_directory_map` - Valid drug-directory pairs
- `ref_drug_indication_clusters` - Drug to SNOMED cluster mapping
### Pathway Tables
- `pathway_date_filters` - 6 pre-defined date filter combinations
- Columns: `id`, `initiated`, `last_seen`, `is_default`, `description`
- Auto-populated via migration
- `pathway_nodes` - Pre-computed pathway hierarchy nodes (~3,600 rows for 12 datasets)
- Routing: `chart_type` ("directory" or "indication"), `date_filter_id`
- Hierarchy: `parents`, `ids`, `labels`, `level`
- Metrics: `value`, `cost`, `costpp`, `cost_pp_pa`, `colour`
- Dates: `first_seen`, `last_seen`, `first_seen_parent`, `last_seen_parent`
- Statistics: `average_spacing`, `average_administered`, `avg_days`
- Denormalized: `trust_name`, `directory`, `drug_sequence`
- Foreign key: `date_filter_id``pathway_date_filters.id`
- Unique constraint: `UNIQUE(date_filter_id, chart_type, ids)` — critical for INSERT OR REPLACE correctness
- Indexed for: date_filter_id, chart_type, trust_name, directory, level
- `pathway_refresh_log` - Tracks data refresh status
- Columns: `refresh_id`, `started_at`, `completed_at`, `status`, `records_processed`, `error_message`, `source_row_count`
## Input Data Requirements
The input data (CSV/Parquet) must contain columns including:
- `Provider Code`, `PersonKey` - Used to create UPID
- `PseudoNHSNoLinked` - NHS pseudonym for GP record matching (indication charts)
- `Drug Name`, `Intervention Date`, `Price Actual`
- `OrganisationName`
- Various `Additional Detail/Description` columns for directory extraction
- `Treatment Function Code`
## Output
Two-view Dash application with distinct analytical perspectives:
**Patient Pathways View** (2 tabs):
1. **Icicle** — Hierarchical pathway view (Directory: Trust → Directorate → Drug → Pathway; Indication: Trust → GP Diagnosis → Drug → Pathway)
2. **Sankey** — Drug switching flows across 1st → 2nd → 3rd treatment lines
Patient Pathways supports:
- Directory / Indication toggle
- Date filter combinations (6 options)
- Trust, drug, and directorate filters via modals
- Lazy rendering (only active tab computed)
**Trust Comparison View** (6 charts in dashboard):
Landing page with directorate/indication buttons → 6-chart dashboard for selected directorate:
1. **Market Share** — Drug breakdown per trust (stacked bars)
2. **Cost Waterfall** — Per-trust cost within directorate
3. **Dosing** — Drug dosing intervals by trust
4. **Heatmap** — Trust × drug matrix
5. **Duration** — Drug durations by trust
6. **Cost Effectiveness** — Pathway costs within directorate (not split by trust)
Trust Comparison supports:
- Directory / Indication toggle (changes landing page buttons)
- Date filter combinations (6 options)
- All 6 charts scoped to selected directorate
## Testing
```bash
# Run all tests with coverage
python -m pytest tests/ -v --cov=core --cov=analysis
# Run specific test file
python -m pytest tests/test_config.py -v
# Run specific test class
python -m pytest tests/test_data_transformations.py::TestPatientId -v
```
Test coverage includes:
- PathConfig validation (23 tests)
- AnalysisFilters validation (26 tests)
- Data transformation functions (23 tests)
- Directory assignment logic (19 tests)
## Configuration
### Snowflake Connection (`src/config/snowflake.toml`)
```toml
[snowflake]
account = "your-account"
database = "DATA_HUB"
schema = "CDM"
warehouse = "your-warehouse"
authenticator = "externalbrowser" # Required for NHS SSO
```
### Logging
Logs are written to `logs/` directory with structured format.
Configure via `src/core/logging_config.py`.
## Breaking Changes from Original App
The pre-computed pathway architecture introduces these changes:
### Date Filters
- **Old**: Date pickers for arbitrary `start_date` and `end_date`
- **New**: Two dropdowns:
- "Treatment Initiated": All years, Last 2 years, Last 1 year
- "Last Seen": Last 6 months, Last 12 months
- **Reason**: Pre-computed pathways require fixed date combinations for performance
### Data Refresh
- **Old**: Real-time pathway calculation on each filter change
- **New**: Pre-computed pathways stored in SQLite, refreshed via CLI command
- **Impact**: Data is as fresh as the last `python -m cli.refresh_pathways` run
- **Benefit**: Sub-50ms filter response time vs multi-minute calculations
### State Management (Dash)
- State lives in 4 `dcc.Store` components: `app-state`, `chart-data`, `reference-data`, `active-tab`
- Filter state: `chart_type`, `initiated`, `last_seen`, `date_filter_id`, `selected_drugs`, `selected_directorates`, `selected_trusts`
- View state: `active_view` ("patient-pathways" | "trust-comparison"), `selected_comparison_directorate` (null | directorate name)
- Chart type toggle: "By Directory" / "By Indication" pills in global sub-header
- Drug/trust/directorate selection via `dmc.Modal` dialogs (Patient Pathways only)
- Fraction KPIs in header (X/X patients, X/X drugs, £X/£X cost)
### Icicle Chart (Patient Pathways)
- Full 10-field customdata structure (value, colour, cost, costpp, first_seen, last_seen, first_seen_parent, last_seen_parent, average_spacing, cost_pp_pa)
- NHS blue gradient colorscale: Heritage Blue #003087 → Pale Blue #E3F2FD
- Treatment statistics (average_spacing, cost_pp_pa) in hover tooltips
- First/last seen dates for drug nodes
- `create_icicle_from_nodes()` in `src/visualization/plotly_generator.py` — shared function accepting list-of-dicts
## Development
### Adding New Analysis Features
1. Add statistical functions to `src/analysis/statistics.py`
2. Integrate into pipeline in `src/analysis/pathway_analyzer.py`
3. Update visualization in `src/visualization/plotly_generator.py`
### Adding New Reference Data
1. Add CSV file to `data/` directory
2. Define schema in `src/data_processing/schema.py`
3. Create migration function in `src/data_processing/reference_data.py`
4. Add path to `PathConfig` in `src/core/config.py`